Antioxidant activity of red rose leaves (Rosa chinensis jacq.) extract

  • Deviyanthi Nur Afifah Department of Pharmacy, Indonesian Health Institute, North Jakarta, Indonesia
  • Yessy Department of Pharmacy, Indonesian Health Institute, North Jakarta, Indonesia
  • Farida Nur Rahmani Department of Pharmacy, Indonesian Health Institute, North Jakarta, Indonesia
  • Ayu Lia Ningsih Department of Pharmacy, Indonesian Health Institute, North Jakarta, Indonesia
  • Citra Dewi Puspita Sari Department of Pharmacy, Indonesian Health Institute, North Jakarta, Indonesia
  • Resna Reformasi Yudapradja Department of Pharmacy, Indonesian Health Institute, North Jakarta, Indonesia
  • Praptiwi Research Center for Chemistry, Indonesian Institute of Sciences, South Tangerang, Banten, Indonesia
  • Rahmawati Ridwan Department of Pharmacy, Indonesian Health Institute, North Jakarta, Indonesia
Keywords: Antioxidant, DPPH, Rosa chinensis Jacq

Abstract

Background: Background: Antioxidants are compounds that can neutralize free radical reactions. The red rose leaves (Rosa chinensis Jacq.), usually disposed of as waste, have been shown to have antioxidant activity. 

Objective: This study aims to determine the antioxidant activity of red rose leaves extracts. 

Methods: The red rose leaves were extracted by the maceration method in ethanol, methanol, ethyl acetate, and n-hexane. The antioxidant activity was measured by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay and was expressed as IC50 and an antioxidant activity index (AAI).

Results: The results showed that the red rose leaves ethanol, methanol, ethyl acetate, and n-hexane extracts had an antioxidant activity with an IC50 value of 1.8, 8.7, 210.3, 48.7 µg/mL, respectively, and an AAI value of 17.3, 3.5, 0.1, 0.6, respectively. The main content of ethanol and methanol extracts are flavonoid, saponin, and tannin.

Conclusion: The ethanol and methanol extract showed the most potent antioxidant activity.

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Published
2020-12-31
How to Cite
Afifah, D. N., Yessy, Rahmani, F. N., Ningsih, A. L., Sari, C. D. P., Yudapradja, R. R., Praptiwi, & Ridwan, R. (2020). Antioxidant activity of red rose leaves (Rosa chinensis jacq.) extract. Acta Biochimica Indonesiana, 3(2), 81-88. https://doi.org/10.32889/actabioina.v3i2.56